Is it possible to add a water cooling system to an older case?

I know it's been a while, also don't know if this has been asked or not yet... but anyways... I'm curious if it's possible to add some type of water cooling system to my build?

I'm in the process of adding a few updates to a previous build.. (about 5 years but still going very very strong) . adding a 2nd GTX960 , and some more RAM. But I got to thinking... can I run a water cooling system in the older Area 51 cases?

And... if there are some maybe list your recommendations?

Thanks in advance.
 

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