The amount of memory has changed

Hi guys any help is appreciated
I am randomly receiving this message at start up: the amount of memory has changed please reseat the memory to fix.
It seems that my memory is intact After checking. But the message come on at random times. I hit continue and then it seems to be okay. I usually shut down the computer and leave it alone for awhile and it wont come back on once i start the computer up.
Please advice what would be the reason and solution for this. Thanks in advance

alienware i7 r4
Gtx 1080
32gb ram


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